外周动脉粥样硬化性狭窄与无症状冠状动脉狭窄相关Association of peripheral atherosclerotic artery disease with asymptomatic coronary artery disease
李南,颜红兵,朱小玲,高海,艾辉,祖晓麟,柯元南
摘要(Abstract)：
目的回顾性分析外周动脉粥样硬化性狭窄与无症状冠状动脉狭窄的关系,为临床实践提供线索。方法根据狭窄部位,将74例患者分为颈内动脉狭窄组(7例)、锁骨下动脉狭窄组(29例)、肾动脉狭窄组(15例)、髂股动脉狭窄组(15例)和多处狭窄组(8例),并观察:(1)单处外周动脉狭窄与无症状冠状动脉狭窄的关系,(2)多处外周动脉狭窄与无症状冠状动脉狭窄的关系,(3)外周动脉狭窄与冠心病高危因素的关系。结果单纯颈内动脉狭窄组(57.1%)、锁骨下动脉狭窄组(51.7%)、肾动脉狭窄组(80.0%)或髂股动脉狭窄组(53.3%)中均有半数以上的患者合并冠状动脉狭窄,其中肾动脉狭窄组更为明显(P<0.05)。多处狭窄组全部8例合并冠状动脉狭窄。结论外周动脉粥样硬化性狭窄但没有冠心病临床表现的患者,可能应当常规行选择性冠状动脉造影,评估是否合并存在冠状动脉疾病。
关键词(KeyWords)： 外周血管疾病;冠状动脉狭窄
基金项目(Foundation):
作者(Author): 李南,颜红兵,朱小玲,高海,艾辉,祖晓麟,柯元南
参考文献(References)：
- 1AqelabRA.Prevalenceofrenalarterystenosisinhigh riskveterans referredtocardiaccatheterization.JHyperten,2003,21:11571161.
- 2Weber MzellD,KotankoP,SchumacherM,etal.Coronaryanatomy predictspresenceorabsenceofrenalarterystenosis.EurHeartJ,2002,23:16841691.
- 3EagleKA,RihalCS,FosterED,etal.Long termsurvivalinpatients withcoronaryarterydisease:importanceofperipheralvasculardisease.TheCoronaryArterySurgeryStudy(CASS)Investigators.JAmColl Cardiol,1994,23:10911095.
- 4ChenWH,HoDSW,HoSL,etal.PrevalenceofExtracranialCarotid andVertebralArteryDiseaseinChinesePatientsWithCoronaryArteryDisease.Stroke,1998,29:631634.
- 5KallikazarosI,TsioufisC,SiderisS,etal.CarotidArteryDiseaseasa MarkerforthePresenceofSevereCoronaryArteryDiseaseinPatients EvaluatedforChestPain.Stroke,1999,30:10021007.
- 6KochM,GradausF,SchoebelFC,etal.Relevanceofconventional cardiovascularriskfactorsforthepredictionofcoronaryarterydiseasein diabeticpatientsonrenalreplacementtherapy.NephrolDial Transplant,1997,12:11871191.
- 7ReisSE,OlsonMB,FriedL,etal.Mildrenalinsufficiencyis associatedwithangiographiccoronaryarterydiseaseinwomen.Circulation,2002,105:28262829.
- 8GradausF,IvensK,PetersAJ,etal.Angiographicprogressionof coronaryarterydiseaseinpatientswithend stagerenaldisease.Nephrol DialTransplant,2001,16:1181202.
- 9OhtakeT,KobayashiS,MoriyaH,etal.Highprevalenceofoccult coronaryarterystenosisinpatientswithchronickidneydiseaseatthe initiationofrenalreplacementtherapy:anangiographicexamination.J AmSocNephrol,2005,16:11411148.