牙齿数目与冠状动脉病变严重程度的关系Association between the number of teeth and the severity of coronary artery disease
康林,刘威,黄超联
摘要(Abstract):
目的研究牙齿数目与冠状动脉病变程度的关系,为冠心病防治提供基础。方法对156例冠心病或可疑冠心病患者通过冠状动脉造影确定冠状动脉病变严重程度,对第3磨牙以外的牙齿进行计数,同时调查其他可能的危险因素。结果冠状动脉评分≥2分组(74例)和冠状动脉评分≤1分组(82例)比较,年龄(65.29±9.23岁比62.04±10.23岁,P=0.04)、糖尿病(32.79%比16.84%、P=0.021)总胆固醇(4.95±0.94mmol/L比4.65±0.90mmol/L,P=0.042)、低密度脂蛋白胆固醇(3.28±0.74mmol/L比2.90±0.78mmol/L,P=0.0020)、高密度脂蛋白胆固醇(1.03±0.29mmol/L比1.16±0.31mmol/L,P=0.009)、C反应蛋白(12.66±14.64mg/L比5.28±5.96mg/L,P<0.001)和牙齿数目(16比23,P<0.001)的差异均有统计学意义,冠状动脉评分≥2分组患者牙齿数目显着少于冠状动脉评分≤1分组。回归分析示牙齿数目对于冠状动脉严重病变的OR值为0.853,95%可信区间0.792~0.918,P=0.001,差异有统计学意义。结论牙周疾病引起的炎症反应与冠心病发病率有关,牙周疾病直接影响牙齿数目,牙齿数目与冠状动脉病变严重程度呈负性相关,防治牙周疾病等口腔疾病可能有益于冠心病预防。
关键词(KeyWords): 牙;炎症;冠状动脉疾病
基金项目(Foundation):
作者(Author): 康林,刘威,黄超联
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