常规血小板糖蛋白Ⅱb/Ⅲa抑制剂与血栓抽吸联用预防急性心肌梗死急诊经皮冠状动脉介入治疗无复流Prevention of no-reflow in acute myocardial infarction patients who received primary percutaneous coronary intervention with routine Ⅱb /Ⅲa receptor antagonist associated with thrombus aspiration
张必利,陈翔,徐荣良,秦永文,郑兴,胡建强,马丽萍,吴弘,陈少萍,陈峰,赵仙先
摘要(Abstract):
目的评价优化急性心肌梗死急诊经皮冠状动脉介入治疗(PCI)策略对减少术中无复流现象发生的效果。方法选择2011年6月至2012年6月第二军医大学附属长海医院心内科急性心肌梗死行急诊PCI患者165例,随机分为经验治疗组[血栓负荷重时才使用血栓抽吸装置和(或)使用血小板糖蛋白Ⅱb/Ⅲa抑制剂]和优化治疗组(无论是否血栓负荷重,均使用血小板糖蛋白Ⅱb/Ⅲa抑制剂+血栓抽吸装置)],观察两组术中无复流的发生率。结果经验治疗组和优化治疗组急诊PCI术中无复流的发生率分别为14%和1.16%(P<0.05)。优化治疗组出血并发症未见增加。结论急性心肌梗死急诊PCI优化治疗策略较经验治疗策略明显减少无复流的发生率,不增加出血并发症的风险。
关键词(KeyWords): 心肌梗死;血管成形术,经腔,经皮冠状动脉;无复流现象;替罗非班
基金项目(Foundation):
作者(Author): 张必利,陈翔,徐荣良,秦永文,郑兴,胡建强,马丽萍,吴弘,陈少萍,陈峰,赵仙先
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