睡眠呼吸障碍与运动时血压变化关系的研究The relationship between sleep apnea-hypopnea syndrome and the variation of blood pressure in exercise
宋以信,中野博,池田东吾,岩永知秋,西间三馨
摘要(Abstract):
目的 阻塞性睡眠呼吸暂停综合征的程度与运动时血压反应的相关分析。方法 将未服用降压药的阻塞性睡眠呼吸暂停综合征患者 49例作为对象 ,用自行车式测量计进行运动试验 ,测量血压、脉搏、血中乳酸值及血气。再将安静时血压、运动负荷时各血压变化量与肥胖指数、临床症状、睡眠多导监测仪检测的夜间血氧饱和度最低值的平均值等数值进行分析。结果 运动负荷时的血压变化量与临床症状、夜间血氧饱和度最低值平均值间显示有相关性 ,而与体重指数无相关性。结论 阻塞性睡眠呼吸暂停综合征的病态程度可能与血压上升有关
关键词(KeyWords): 阻塞性睡眠呼吸暂停综合征;运动;高血压
基金项目(Foundation):
作者(Author): 宋以信,中野博,池田东吾,岩永知秋,西间三馨
参考文献(References):
- 1陈和夫.阻塞性睡眠时无呼吸症候群に关する最新の知见上诸问题.日呼吸会志,1999,37:169176.
- 2SomersVK ,DykenME ,ClaryMp,etal.Sympatheticneualmechanismsinobstructivesleepapnea.JClinInvest,1995,96:18971904.
- 3OtsukaN ,OhiM ,Chink,etal.Assessmentofcardiacsympatheticfunctionwithiosine123MIBGimaginginObstructivesleepapneasyndrome.JNuclMed,1997,38:567572.
- 4BrooksD ,HornerRL ,KozarLF ,etal.ObstructivesleepapneaasacauseofsystemichypertensionEvidencefromacaninemodel.JClinInvest,1997,99:106109.
- 5Narkiewiczk,vandebornePJ,PesekCA ,etal.Selectivepotentiationofperipheralchemoreflexsensitivityinobstructivesleepapnea.Circulation,1999,99:11831189.
- 6Narkiewiczk,vandeBornePJ ,CooleyRL ,etal.Sympatheticactivityinobesesubjectswithandwithoutobstructivesleepapnea.Circulation,1998,98:772776.