两种血管闭合器在冠状动脉介入治疗中的应用比较Safety and efficacy of arterial closure devices (angioseal and perclose) in patients undergoing coronary angiography and angioplasty
刘宇扬,周玉杰,赵迎新,郭永和,成万钧,张世新
摘要(Abstract)：
目的评价并比较Angioseal和Perclose两种血管闭合器在经皮冠状动脉造影(CAG)及介入治疗(PCI)中应用的有效性和安全性。方法1020例行冠脉造影及介入治疗的患者(男672例,女348例,年龄57.8±2.4岁)经髂动脉造影证实无血管闭合器使用禁忌,术后随机分为Angioseal组(CAG380例,PCI120例)和Perclose组(CAG392例,PCI128例),比较两组患者使用血管闭合器的成功率及局部并发症的发生率。结果Angioseal和Perclose两组成功率均较高(94%比96%),差异无统计学意义。Angioseal组发生局部血肿5例,无假性动脉瘤发生;Perclose组发生局部血肿4例,假性动脉瘤3例,两组间并发症的发生率差异亦无统计学意义。结论CAG及PCI术后,Angioseal和Perclose血管闭合器均能有效止血,并发症较低,安全性好。
关键词(KeyWords)： 血管闭合器;血管成形术,经腔,经皮冠状动脉
基金项目(Foundation):
作者(Author): 刘宇扬,周玉杰,赵迎新,郭永和,成万钧,张世新
参考文献(References)：
- 1StarnesBW,DonnellSD,GillespieDL,etal.Percutaneousarterial closureinperipheralvasculardisease:aprospectiverandomized evaluationofthePerclosedevice.JVascSurg,2003,38:263271.
- 2KorenyM,RiedmullerE,NikfardjamM,etal.Arterialpuncture closingdevicescomparedwithstandardmanualcompressionafter cardiaccatheterization:systematicreviewandmeta analysis.JAMA,2004,291:350357.
- 3HeintzenMP,StrauerBE.Peripheralarterialcomplicationsafterheart catheterization.Herz,1998,23:420.
- 4SkillmanJJ,KimD,BaimDSVascularcomplicationsofpercutaneous femoralcardiacinterventions:incidenceandoperativerepair.Arch Surg,1988,123:12071212.
- 5RickliH,UnterwegerM,SutschG,etal.Comparisonofcostsand safetyofasuture mediatedclosuredevicewithconventionalmanual compressionaftercoronaryarteryinterventions.CatheterCardiovasc Interv,2002,57:297302.
- 6WagnerSC,GonsalvesCF,EschelmanDJ,etal.Complicationsofa percu taneoussuture mediatedclosuredeviceversusmanual compressionforarteriotomyclosure:acase controlledstudy.JVasc IntervRadiol,2003,14:735741.
- 7EggebrechtH,NaberC,WoertgenU,etal.Percutaneoussuture mediatedclosureoffemoralaccesssitesdeployedthroughtheprocedure sheath:initialclinicalexperiencewithanovelvascularclosuredevice.CatheterCardiovascInterv,2003,58:313321.