急性心肌梗死经皮冠状动脉介入治疗术后支架内血栓伴血小板减少二例
鲁硕,王亦舒,侯凤霞
摘要(Abstract)：
<正>应用血小板糖蛋白(glycoprotein,GP)Ⅱb/Ⅲa抑制剂(替罗非班)可以降低急性心肌梗死(AMI)经皮冠状动脉介入治疗(PCI)术后支架内血栓发生率,本文报道2例PCI术后出现支架内血栓,应用替罗非班引起严重血小板减少后的治疗策略。病例1,女,75岁,间断胸闷、胸痛6年,加重1 d入院。脑梗死病史7年,入院至病房时血压138/78 mmHg(1 mmHg=0.133 kPa),双肺未闻及干、湿啰音,心界不大,心率70次/min,心律齐,心音弱,各瓣膜听诊区未闻及病理性杂音。入院急诊心电图(图1)异位心律,心律失常,心房颤动,Ⅱ、Ⅲ、aVF导联T波倒置,V1~V4导联ST段抬高0.2~0.4 mV,至病房时心电图恢复窦性心律。实验室检查:低密度脂蛋白胆固醇(LDL-C)2.49 mmol/L,
关键词(KeyWords)： 经皮冠状动脉介入治疗;支架内血栓;血小板
基金项目(Foundation):
作者(Author): 鲁硕,王亦舒,侯凤霞
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